AstraZeneca, the announcement of a team of researchers: “The cause of the rare cases of thrombosis has been discovered”

A team of scientists from Wales and the United States announced that they have found the underlying cause of the very rare blood clots caused by AstraZeneca’s Covid vaccine. According to reports from the Bbc, the team of researchers was able to show how a protein present in the blood is attracted to a key component of the Oxford vaccine, triggering a reaction that involves the immune system and which can culminate in blood clots. “What we have is the trigger, but there are many steps that still need to be understood,” explained Alan Parker, one of the Cardiff University researchers who worked on the study. The study published in the scientific journal Science Advances it is presented by the team of scientists as “research that is not definitive but offers interesting insights in an attempt to remove this extremely rare side effect”. At the moment the University of Oxford, from which the original trial of the Covid vaccine comes, has preferred not to comment on the results published by the group of American and Welsh scientists.

“As part of the largest vaccination campaign in history, ultrarary side effects not seen in phase 3 studies were observed, including thrombosis with thrombocytopenia syndrome (TTS), a rare condition similar to heparin-induced thrombocytopenia (HIT)” , writes the team of the latest study on AstraZeneca, explaining how all three adenoviruses used as vaccination vectors with respect to SARS-CoV-2 bind to the so-called platelet factor 4 (PF4), a protein implicated in the genesis of thrombocytopenia itself. AstraZeneca was one of the most used products in the UK in the very first months of the vaccination campaign and also in Italy it initially represented the largest supply of doses purchased compared to all other productions. Due to the rare dangers of blood clots the use of the Oxford product was then reduced. Still for the recall campaign it is replaced by one of the two mRna vaccines, Pfizer or Moderna.

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AstraZeneca announcement team researchers rare cases thrombosis discovered

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