In those who have been vaccinated against the Covid the possibility of being infected by Sars-Cov-2 is clearly reduced and even if the infection occurs, viral load and febrile symptoms are much lower and last less compared to what happens in those who become infected without being covered by the vaccine. This was highlighted by a large study, published in preprint on the Medrxiv server and being published in a scientific journal, conducted on people who developed infections despite being vaccinated.
Covid vaccines were first developed to reduce mortality and severe forms, but more and more studies are focusing on aspects that, although not among the primary objectives of clinical trials, are nevertheless very important in terms of public health. . In this case, the team, led by Mark Thompson of the Centers for Disease Control and Prevention (CDC), surveyed 3,975 health workers and first responders at eight locations across the United States between December 2020 and May 2021. 204 (5.1%) of the participants who had a Sars-CoV-2 infection in this time frame, of which 16 partially or fully vaccinated and 156 unvaccinated.
Complete vaccination with mRna vaccine was 91% effective in preventing Sars-CoV-2 infection, while in those who had one dose the effectiveness in preventing infection dropped to 81%. The mean viral load of RNA detected was 2.3 among the partially or fully vaccinated participants, compared to 3.8 among the unvaccinated; the analysis showed a 40.2% lower viral RNA load after at least one partial vaccination. Only 25% of people who were at least partially vaccinated reported fever compared to 63% of unvaccinated, meaning a 58% reduction in the risk of febrile symptoms was seen. Finally, the vaccinated also reported 6.4 days less discomfort than the unvaccinated. HANDLE
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