Myocarditis and pericarditis potentially associated with mRNA vaccination against Covid-19, and in particular with preparations developed by Pfizer-BioNTech and Moderna, are rare events, with generally mild and favorable outcomes. This is what is reported in an Expert Opinion of the Italian Society of Cardiology, published in the Italian Journal of Cardiology and signed by about fifteen experts, including Gianfranco Sinagra of the Cardiomyopathies Diagnosis and Treatment Center of the University of Trieste, Giuseppe Mercuro of the Department of Medical Sciences and Public Health of the University of Cagliari, and Pasquale Perrone Filardi of the Department of Advanced Biomedical Sciences of the University of Naples. (LATEST NEWS LIVE – COVID VACCINE: DATA AND GRAPHICS ON ADMINISTRATIONS IN ITALY, REGION BY REGION)
Incidence: 1 case per 100 thousand individuals
Coronavirus in Italy and in the world: news today 27 September. LIVE
The study, in particular, reveals that the estimated incidence of these rare adverse events is 1 case per 100 thousand individuals, or more than 10 times lower than that of myocarditis not attributable to vaccines (with an incidence of 10-20 cases per 100 thousand people ).
Experts also report that, without prejudice to the rare nature of the event, the estimated rate appears to be higher in people under the age of 30, who have completed vaccination and of male sex (40 per million among men and 4 , 2 among women). Among the over 30s, on the other hand, the rates drop to 2.4 per million among men and 1.0 per million among women. “The risk / benefit balance is clearly in favor of vaccination against Covid: in unvaccinated subjects and with Sars-CoV-2 myocarditis and pericarditis are in the order of 11 cases compared to 2.7 cases in 100 thousand. monitor males under the age of 30 who complete the vaccination cycle “, explain the experts, underlining that the study proposes for the first time” a nosographic classification of “post-vaccine” forms, facilitating their identification and the construction of registers research and provides guidelines for mRNA vaccination in specific subgroups of the population “.
Finally, the Expert Opinion reiterates the important role played by vaccines in the fight against the Covid-19 pandemic, which in just over a year caused 2.69 million deaths and 122 million infections. Vaccines have in fact significantly contributed to reducing morbidity and mortality rates.