During these weeks many are struggling with calculations and reservations: the goal is to try to go on vacation making sure that the dates of vaccines and booster do not overlap with those of the holiday. But is it possible to leave safely after taking the first dose? In reality, the news coming from the United Kingdom is not too comforting: in Great Britain the infections from Covid are increasing due to the spread of the Delta variant, that is the Indian one, which is now prevalent over the English one. The problem, according to a study published in the Lancet, is that in people who have received only one dose of Pfizer, the antibody response against this new strain of Covid appears to be lower. Pfizer produces lower levels of antibodies against the Delta variant. But there is also good news: the drug is effective against all types of Sars-Cov-2 after the second dose.
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The virologist Roberto Burioni pointed out that «with two doses, antibodies are induced that neutralize all the variants of Sars-CoV-2, while with only one no. And this could explain why the Brazilian and Indian variants are circulating in England ». Burioni added that “a single dose of Pfizer vaccine induces a good amount of neutralizing antibodies against the original virus in most vaccines. On the contrary, that single dose of vaccine does not induce such an effective response against the variants, in particular the Brazilian and the Indian ». For this reason, after the first administration it is necessary to continue to scrupulously respect the anti-contagion prescriptions: wear masks, sanitize your hands frequently, avoid crowded places, respect interpersonal distances.
In these days, in Italy we are witnessing a sharp decline in deaths and infections, but the emergency is not over. As far as travel is concerned, if you go abroad it is important to consult the «Traveling safe» portal of the Ministry of Foreign Affairs to understand the situation in other countries and take any precautions.
Then there is another non-secondary question: many are wondering if it will be possible to receive the second dose of vaccine in the vacation places. For the moment, the most likely hypothesis is that this possibility – in Italy – will be reserved for those who will spend a long period of time away from home, since it would be too chaotic to organize a mass vaccination in holiday resorts.
Another hypothesis, more practicable, is to postpone the appointment for the recall by a few days. However, each drug has a different flexibility threshold for booster. According to the indications of the Italian Medicines Agency (Aifa), the second dose of Pfizer can be performed after a minimum of 21 and a maximum of 42 days from the first injection. For Moderna it goes from 28 to 42 days, while for AstraZeneca the recall should be done after a minimum of 70 and a maximum of 84 days.
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