Covid vaccines, 400 thousand doses of Moderna – Chronicle arrive

Milan – Beyond 400 thousand doses of the Moderna vaccine I am arriving this evening at the national defense hub at the military airport of Pratica di Mare, near Rome. Good news, given that the lot will be distributed to the Regions starting tomorrow. It is the least used product in Italy. According to the British newspaper Guardian, the US company has production problems in Europe and this could affect deliveries both in the EU and in the United Kingdom and Canada. In the meantime, the vaccination campaign is accelerating and, despite the different vaccination trends in the regions, we can see the first effects of vaccines on the data of hospitalized and infected people in these age groups, as pointed out by the president of the Higher Institute of Health Silvio Brusaferro: “The median age at diagnosis and at the time of admission is decreasing, which means that even indirectly we are starting to see the first effects of vaccinations for the elderly. People over the age of 80 but also the seventies begin to decrease in the number of cases “.

There are 14,785,115 doses of vaccine against Covid-19 so far administered in Italy, 85.3% of the total of those delivered, equal to 17,323,080 (in detail 11,845,080 Pfizer / BioNTech, 1,320,400 Moderna and 4,157,600 AstraZeneca). The administrations involved 8,607,817 women and 6,177,298 men. 4,374,184 people have received both doses, while about ten and a half million have received at least one dose, 17.5% of the population. The doses were administered to 3,202,860 health workers, 533,802 non-health personnel, 611,031 residents of residential structures, 5,053,069 over 80, then 237,211 units of the armed forces, 1,131,878 units of school personnel. The ‘other’ item includes 4,015,264 people.

And yesterday there was a record in Italy: in just one day 347,279 doses of the vaccine were administered in Italy, according to data provided by the Office of the Emergency Commissioner, General Francesco Paolo Figliuolo. IS Health Minister Roberto Speranza promises: “We will accelerate again in the coming weeks”.

As for the age groups, coverage of over 80s has risen: over 76% of the 4.5 million over 80s received one dose of the vaccine, while 45% received both doses. However, strong regional differences remain. According to the latest government report, the Marches have administered a dose to 100% of the over 80. Followed by the Autonomous Province of Trento (91%), Emilia Romagna and Veneto (87%), Lombardy (83%), Basilicata and Tuscany ( 82%), Piedmont (81%), all above 80%. Ten regions below the national average: the worst are Sicily (51%), Calabria (54%), Sardinia (65%), Abruzzo and Liguria (66%), Campania (68%), all below 70%. For the second doses, the autonomous provinces of Trento (67%) and Bolzano (65%) are the only ones above 60%, while Tuscany (31%), Sardinia (32%), Sicily (34%) are below 40%. ), Calabria (37%), Umbria (39%).

Meanwhile, in Lombardy, reservations for the over 65 age group are about to start, from the day after tomorrow 19 April. As for the over 70s, just over 30% received a dose of the vaccine while the data on second doses is still low (3.4%).

On the Italian territory, the vaccination plan is being implemented with very varied scenarios. In Sicily, the Open Weekend launched by the Region, with AstraZeneca even without reservations for 60-79 year olds, ha led to quadruple the doses normally administered. Directly to the injection site also in Taranto for the 70-79 year old group, with a good success of the initiative. In Sardinia, on the other hand, the IT system of the hubs went haywire and the health card data were recorded on paper by the operators, resulting in long queues. The next phase of the vaccination campaign will concern the under 60s, the age group so far considered less at risk of serious consequences for the virus.

The regions, sheltered over 60 and fragile, as imposed by the government, will have some freedom on how to proceed. Del Lazio, one of the most effective in the first phase, it is already known that it will continue to follow the demographic criteria and will open AstraZeneca – recommended for over 60s – also to under 60s on a voluntary basis. Also in Friuli Venezia Giulia the registry office will be followed: if the government provisions do not change, the starting point will be 55-59 years old. The Campania of Vincenzo De Luca confirms the double track: decreasing age group and strategic categories, like tourism operators in view of the summer.
At the moment it is a hypothesis, because, as the Region of Sicily says, “we have advanced our proposals to Commissioner Figliuolo and we are waiting for the green light”. In Basilicata, after the elderly and the frail – assures the governor Vito Bardi – it will be the turn of all the workers who have been at the forefront of the pandemic. In Liguria, on the other hand, there is already a calendar: from 11 May reservations for 55-59 year olds and on until 15 June when 40-44 year olds can be prepared. Vaccination of 60-year-olds is already underway in South Tyrol. Barring unforeseen events, at the beginning of May it is expected to pass to the age of 50. In Puglia the goal is also to call the over 60s by 18 July, and then move on to the under 60s. But given the low adhesion of over 60s, the next phase could start earlier. Among the other larger and more populous Regions, Lombardy for the vaccination of the under 60s will go from 210 current centers to 76 maxi-hubs in the various provinces. With the supplies provided, 50-59 year olds (over 1.5 million and a half) will be able to book from April 30 and be vaccinated from mid-May; from 49 years old (over 4 million) booking after mid-May and administration from June. In Veneto it will be up to the under 60s after the summer. There are no certain dates yet. An online program will be available shortly to find out the exact period from 16 years of age. Finally, in Umbria we only know that the under 60s will all be vaccinated with Pfizer.

The first doses of the vaccine were expected to arrive this week produced by Johnson & Johnson, considered a turning point because single-dose. To give an abrupt stop to its debut in the vaccination campaign was the suspension by the US Food and Drug Administration after 6 suspected cases of rare thrombosis found in more than 6.8 million vaccinated. It is the same type of adverse and rare reaction found in the AstraZeneca vaccine and that has brought many implications on the progress of the vaccination campaign, including temporary suspensions, age limits and renunciations of the population.

The first 184 thousand doses of Johnson & Johnson destined for Italy remained at the national hub of Pratica di Mare and the company’s deliveries in Europe were suspended. The EMA is investigating closely with the FDA, it should rule on it next week, but at the moment it considers the benefits outweigh the risks.

French Industry Minister Agnes Pannier-Runacher said the European Union is likely not to renew contracts with AstraZeneca and Johnson & Johnson, preferring mRNA-based vaccines such as Pfizer, Moderna and the next expected to market and manufactured by the company tedesca Curevac. The President of the Commission Ursula von der Leyen announced that Pfizer has the delivery of 50 million doses has been brought forward to the current quarter (in addition to the other 10 already anticipated) and that a contract for the supply of 1.8 billion doses is already being negotiated for the three-year period 2021-2023, after a third recall is being feared due to the variants. In the rest of Europe, the largest states such as France, Germany and Spain are driving the pace of the vaccination campaign: the “milestone”, as defined by Von der Leyen, of the 100 million doses administered. THEn Spain and Germany 19% of the population received the first dose, while in France 17.6%, compared to 17% in Italy.

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